Kathryn Miller-Jensen

Kathryn Miller-Jensen


Lab Website
Associate Professor of Biomedical Engineering & Molecular, Cellular & Developmental Biology
Room / Office: Malone 311
Office Address:
55 Prospect Street
New Haven, CT 06511
Mailing Address:
P.O. Box 208260
New Haven, CT 06520
Phone: (203) 432-4265
Email: kathryn.miller-jensen@yale.edu
  • Ph.D., Massachusetts Institute of Technology
  • A.B., B.E., Dartmouth College


Dr. Miller-Jensen's research uses quantitative, systems-level approaches to study intracellular and extracellular signaling networks regulating immune cell functions. Her lab is particularly interested in how variability between single cells impacts immune responses. Research projects in the lab focus on the regulation of macrophage activation in response to pathogenic stimulation and within tumor microenvironments; and how signaling networks regulate the reactivation of latent HIV in T cells.

Selected Awards & Honors:

  • NSF CAREER Award (2015)
  • Cellular and Molecular Bioengineering Young Innovator (2014)
  • SEAS Ackerman Award for Teaching and Mentoring (2014)
  • NRSA Postdoctoral Fellowship, National Institutes of Health (2008-2011)
  • Science & Technology Policy Fellow, The National Academies (2006)

Selected Publications:

  • Gaudet S* and Miller-Jensen K*. Redefining signaling networks with an expanding single-cell toolbox, Trends in Biotechnology, 34(6): 458-69 (2016)
  • Xue Q, Lu Y, Eisele MR, Sulistijo E, Fan R*, and Miller-Jensen K*. Analysis of single-cell secretion reveals a role for paracrine signaling in coordinating macrophage response to TLR4 stimulation, Science Signaling, 8:381 (2015)
  • Ramji R, Wong, VC, Chavali, AK, Gearhart L, Miller-Jensen K. A passive-flow microfluidic device for imaging latent HIV activation dynamics in single T cells, Integrative Biology, 7(9): 998-1010 (2015)
  • Lu Y, Xue Q, Eisele MR, Sulistijo E, Brower K, Han L, Amir ED, Pe'er D, Miller-Jensen K *, and Fan R*, Highly multiplexed profiling of immune effector functions reveals deep functional heterogeneity in response to pathogenic ligands, Proc. Natl. Acad. Sci., U.S.A., 112(7): 607-615 (2015)
  • Chavali AK, Wong VC, and Miller-Jensen K. Distinct promoter activation mechanisms modulate noise-driven HIV gene expression, Scientific Reports, 15(5): 17661 (2015)